DRL - Otago University
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Ongoing work continues to explore alternative immunodiagnostic tests for the management and eradication of mycobacterial diseases in ruminants.

Research in the Disease Research Labooratory (DRL) targets immunity to mycobacterial infections in domestic livestock (sheep and deer) and wildlife (Cape buffalo). All facets of immunity to infection including improved diagnosis, vaccination and selection for heritable resistance are studied.

Diagnostic tests developed by DRL under Professor Griffin's directorship, are used extensively for immune profiling of Mycobacterial diseases in ruminants. The main diseases being studied are Tuberculosis (TB); caused by Mycobacterium bovis and Johne's disease (JD); caused by Mycobacterium paratuberculosis.


Griffin, J.F.T., Chinn D.N and Rodgers C.R. Diagnostic Strategies and Outcomes on three New Zealand Deer Farms with Severe Outbreaks of Bovine Tuberculosis. Tuberculosis 84: 293-302 (2004)

O'Brien, R., Rodgers, C., Liggett, S., Spittle, E., Crosbie, P and Griffin, F. Immunodiagnosis of TB and Johne's disease in deer. Proc NZVA Deer Br. 21: 102-105 (2004).

Chinn, N., Rodgers, C., Liggett, S., Spittle, E and Griffin, F. An Alternative IgG1 ELISA for Tb Diagnosis in Deer. Proc NZVA Deer BR. 19: 81-89 (2002)

Griffin, J. F. T., Chinn, N. G. Mc Kenzie, J. Liggett, S. and Rodgers, C. R. Advances in Tb diagnosis and prevention: lessons gained from the New Zealand deer industry. Proc NZVA Deer Br. 17 203-208 (2000)

Griffin, J.F.T., Cross, J.P., Chinn, D.N., Rodgers, C.R. and Buchan, G.S. Diagnosis of Tuberculosis due to M.bovis in New Zealand Red Deer (Cervus elaphus) using a composite blood test (BTB) and antibody (ELISA) assays. N.Z. Vet. J. 42:173-179 (1994)
 
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Practical application of the work done by DRL has resulted in a diagnostic facility available for the National deer herd Tb testing programme. Several tests are offered to the farming sector by DRL: Tb Diagnostics ETB (IgG1 ELISA for TB in deer) Johne's disease diagnostics PARALISA™ (IgG1 ELISA for JD in deer)

DRL - Otago University
Disease Research Laboratory
4th Floor (414) Microbiology Department
University of Otago
720 Cumberland Street
Dunedin
Ph: 03 479 7710
03 477 2160

drl@otago.ac.nz Click here for Our Website
Postal Address
Disease Research Laboratory
University of Otago
P O Box 56
Dunedin 9016


Other Contact Details
 
Professor Frank Griffin
Director
Simon Liggett
Technical Manager
Disease Research Laboratory +6434797710

PARALISA™ Laboratory Request Form ETB Laboratory Request Form